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CAS No 125472-02-8 , 2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide

  • Name: 2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide
  • Synonyms: ucb 22073; Benzamide,2-hydroxy-3-(1H-imidazol-5-ylmethyl)-; 125472-02-8; Closantel 6; Mivazerolum;Mivazerolum [INN-Latin];2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide; mivazerol[inn];
  • CAS Registry Number:
  • Flash Point: 252.1°C
  • Boiling Point: 493.3°C at 760 mmHg
  • Density: 1.379g/cm3
  • Refractive index: 1.67
  • Flash Point: 252.1°C
  • Molecular Weight: 217.22394
  • InchiKey: RLHGFJMGWQXPBW-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H11N3O2/c12-11(16)9-3-1-2-7(10(9)15)4-8-5-13-6-14-8/h1-3,
    5-6,15H,4H2,(H2,12,16)(H,13,14)
  • Molecular Formula: C11H11N3O2
  • Molecular Structure:CAS No:125472-02-8 2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide

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125472-02-8 Mivazerol

  • Mivazerol, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
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125472-02-8 125472-02-8

  • 125472-02-82-Hydroxy-3-(1H-imidazol-4-ylmethyl)-benzamide, >97%
  • United States Greenchem Institute [Importer/Exporter]
  • Tel: 610 642 1716 (202) 872-4600
  • Address: 1155 Sixteenth Street, NW Washington, DC 20036 USA Washington,DCUnited States
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References of 2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide
Title: Mivazerol
CAS Registry Number: 125472-02-8
CAS Name: 2-Hydroxy-3-(1H-imidazol-4-ylmethyl)benzamide
Synonyms: a-imidazol-4-yl-2,3-cresotamide
Molecular Formula: C11H11N3O2
Molecular Weight: 217.22
Percent Composition: C 60.82%, H 5.10%, N 19.34%, O 14.73%
Literature References: a2-Adrenergic agonist. Prepn: E. Cossement et al., EP 341231; eidem, US 4923865 (1989, 1990 both to UCB); idem et al., J. Pharm. Belg. 49, 206 (1994). Specificity for a2 adrenoceptors and binding studies: M. Noyer et al., Neurochem. Int. 24, 221 (1994). Clinical trial to improve perioperative hemodynamic stability: D. T. Mangano et al., Anesthesiology 86, 346 (1997). Mode of action study: M. Guyaux et al., Acta Anaesthesiol. Scand. 42, 238 (1998).
Properties: mp 197.6°.
Melting point: mp 197.6°
 
Derivative Type: Hydrochloride
CAS Registry Number: 127170-73-4
Manufacturers' Codes: UCB-22073
Molecular Formula: C11H11N3O2.HCl
Molecular Weight: 253.68
Percent Composition: C 52.08%, H 4.77%, N 16.56%, O 12.61%, Cl 13.98%
Properties: mp 287.8°. LD50 i.p. in mice: 760 mg/kg (Cossement).
Melting point: mp 287.8°
Toxicity data: LD50 i.p. in mice: 760 mg/kg (Cossement).
 
Therap-Cat: To reduce cardiac complications of surgery.
Keywords: a-Adrenergic Agonist.