Home > Name List By other > (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

CAS No 107868-30-4 , (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,
16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Name: (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthrene-3,17-dione
  • Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione; 107868-30-4; Exemestano [INN-Spanish]; Exemestanum [INN-Latin];(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthrene-3,17-dione; Exemestance;Aromasin;
  • CAS Registry Number:
  • Melting Point: 155.13 ºC
  • Flash Point: 169 ºC
  • Boiling Point: 453.7 ºC at 760 mmHg
  • Density: 1.13 g/cm3
  • Refractive index: 1.572
  • Safety Statements: Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating vapors.
  • Hazard Symbols: A reproductive hazard.
  • Flash Point: 169 ºC
  • Molecular Weight: 296.40336
  • InchiKey: BFYIZQONLCFLEV-DAELLWKTSA-N
  • InChI: InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,
    3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,
    2-3H3/t14-,15-,16-,19+,20-/m0/s1
  • Molecular Formula: C20H24O2
  • Molecular Structure:CAS No:107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,<br />16-octahydrocyclopenta[a]phenanthrene-3,17-dione

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107868-30-4 Exemestane

  • Product Name:Exemestane CAS NO.:107868-30-4 Other Name: Aromasin; 6-Methylenandrosta-1,4-diene-3,17-dione Molecular Formula: C20H24O2 Molecular weight: 296.40 Assay: 99% Appearance: white to almost white powder Aromasin is used to fight breast cancer...
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107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Data of Exemestane Powder: Exemestane ( Aromasin ) Alias: Exemestan; Trade name: Aromasin. Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99%...
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107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Exemestane ( Aromasin ) Alias: Exemestan; Trade name: Aromasin. Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99% Exemestane ( Aromasin ) Me...
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107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Exemestane ( Aromasin ) Alias: Exemestan; Trade name: Aromasin. Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99% Exemestane ( Aromasin ) Me...
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107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Exemestane ( Aromasin ) Alias: Exemestan; Trade name: Aromasin. Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99% Exemestane ( Aromasin ) Me...
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107868-30-4 (8ta[a]phenanthrene-3,17-dione

  • Exemestane ( Aromasin ) Alias: Exemestan; Trade name: Aromasin. Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99%
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107868-30-4 (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15, 16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Exemestane ( Aromasin ) CAS ID: 107868-30-4 Exemestane ( Aromasin ) MF: C20H24O2 Exemestane ( Aromasin ) MW: 296.4 Exemestane ( Aromasin ) Aromasin Purity: 99% Exemestane ( Aromasin ) Melting point: 155.13°C Exemestane ( Aromasin ) Appearance: white ...
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107868-30-4 Exemestane

  • Exemestane is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body’s muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estroge...
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107868-30-4 Exemestane

  • Exemestane(CAS No.: 107868-30-4) Synonyms:Exemestane,powder,hormone,steroid,Exemestane [USAN:INN:BAN];Aromasil;Aromasin;FCE 24304;Exemestane Tablets Formula: C20H24O2 Molecular Weight: 296.41 Purity:99% Appearance: white to light yellow crystal powde...
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107868-30-4 sell Exemestane apple_zhl@hotmail.com

  • Product name:Exemestane CAS:107868-30-4 Purity: 99.8 Appearance:white powder Package: 1kg/ Aluminum foil bag Application: Research purpose Production Capacity: 500 Kilogram/Month Storage: Kept in a cool, dry and ventilated place Please contact: apple...
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References of (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,
16-octahydrocyclopenta[a]phenanthrene-3,17-dione
Title: Exemestane
CAS Registry Number: 107868-30-4
CAS Name: 6-Methyleneandrosta-1,4-diene-3,17-dione
Manufacturers' Codes: FCE-24304
Trademarks: Aromasin (Pharmacia & Upjohn)
Molecular Formula: C20H24O2
Molecular Weight: 296.40
Percent Composition: C 81.04%, H 8.16%, O 10.80%
Literature References: Irreversible aromatase inhibitor. Prepn: E. Di Salle et al., DE 3622841; F. Buzzetti et al., US 4808616 (1987, 1989 both to Farmitalia Carlo Erba). Pharmacology: D. Giudici et al., J. Steroid Biochem. 30, 391 (1988). HPLC determn in plasma: M. Breda et al., J. Chromatogr. 620, 225 (1993). Clinical pharmacology: T. R. J. Evans et al., Cancer Res. 52, 5933 (1992). Review of clinical experience in primary and secondary therapy for breast cancer: J. M. Dixon, Expert Rev. Anticancer Ther. 2, 267-275 (2002). Clinical trial in sequential therapy following tamoxifen in breast cancer: R. C. Coombes et al., N. Engl. J. Med. 350, 1081 (2004).
Properties: White to slightly yellow crystalline powder. mp 188-191°. uv max: 247 nm (e 13750). Freely sol in DMF; sol in methanol. Practically insol in water.
Melting point: White to slightly yellow crystalline powder. mp 188-191°
Absorption maximum: uv max: 247 nm (e 13750)
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Aromatase Inhibitors; Aromatase Inhibitors.