Home > Name List By 3 > 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6, 7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one

CAS No 106266-06-2 , 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,
7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one

  • Name: 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,
    7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
  • Synonyms: Risperidal M-Tab; Risperin; Sequinan; Rispolept; Rispolin;Risperdal; Risperdal M-Tab;3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,
    7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one; Risperdal Consta; Risperidal;
  • CAS Registry Number:
  • Transport: 25kgs
  • Density: 1.38 g/cm3
  • Refractive index: 1.676
  • Safety Statements: 28-36-45
  • Hazard Symbols: T: Toxic;
  • Molecular Weight: 410.484483
  • InchiKey: RAPZEAPATHNIPO-UHFFFAOYSA-N
  • InChI: InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-
    7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,
    1H3
  • Risk Statements: 25
  • Molecular Formula: C23H27FN4O2
  • Molecular Structure:CAS No:106266-06-2 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,<br />7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
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106266-06-2 Risperidal

  • Product Risperidal and Intermediates CAS NO 106266-06-2 Standard Enterprise Standard Molecular Formula C23H27FN4O2 Molecular Weight 410.48 Description off-White or white crystal or crystalline powder Package 25KG/drums Application schizophrenia
  • China Jinan Jianfeng Chemical Co.Ltd [Manufacturer]
  • Tel: 86-531-88110457
  • Fax: --
  • Address: NO9. Hua Neng Road, Jinan, China Jinan,ShandongChina

106266-06-2 Risperidal

  • Risperidal Synonyms:RISPERDAL;RISPERIDAL;RISPERIDONE;BELIVON Product Categories:Active Pharmaceutical Ingredients;API;APIs;Risperidone;Inhibitors; CAS:106266-06-2 Appearance:whiteCrystalline Solid Purity:99% Package:5kg/cardboard MF:C23H27FN4O2 MW:41...
  • Min. Order: 10
  • FOB Price: USD1 - 1 /
  • China Raw Steroid Main Shop [Manufacturer]
  • Tel: 86-0731-22290207
  • Fax: --
  • Address: Hunan zhuzhou,HunanChina
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106266-06-2 Risperidone

  • product Name risperidone Synonyms 3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one; Risperidone intermediates; Risperidal; Resperidone; 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)pi...
  • Min. Order: 1000
  • China Merry Pharmtech Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-183-67150305
  • Fax: 86-183-67150305
  • Address: Linan Area hangzhou,ZhejiangChina
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106266-06-2 Risperidone

  • Product Name: Risperidal Synonyms: 4h-pyrido(1,2-a)pyrimidin-4-one,6,7,8,9-tetrahydro-3-(2-(4-(6-fluoro-1,2-benzi;soxazol-3-yl)-1-piperidinyl)ethyl)-2-methyl-;R-64766;RISPERDAL;RISPERIDAL;RISPERIDONE;BELIVON;3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1...
  • Min. Order: 1
  • FOB Price: USD1 - 100 /
  • China Wuhan Senwayer Century Chemical Co.,Ltd [Manufacturer]
  • Tel: 86-027-59707018
  • Address: 20#Xudong Street,Wuhan China Wuhan,HubeiChina
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106266-06-2 Risperidone CAS 106266-06-2 and Its Intermediates

  • Risperidone and its intermediates 1. Risperidone 106266-06-2 99% 2. 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride 84163-13-3 99% 3. (Z)-(2,4-difluorophenyl)-4-piperidinyl-Methanone oxime 691007-05-3 98%
  • China Shanghai Twisunpharm Co,. Ltd [Manufacturer]
  • Tel: 86-021-54590859
  • Fax: --
  • Address: No.188, Jinou Road, Jinshan District, Shanghai Shanghai,ShanghaiChina
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106266-06-2 Risperidone

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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106266-06-2 Risperidone

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106266-06-2 Risperidal

  • Product Risperidal and Intermediates CAS NO 106266-06-2 Standard Enterprise Standard Molecular Formula C23H27FN4O2 Molecular Weight 410.48 Description off-White or white crystal or crystalline powder Package 25KG/drums Application schizophrenia
  • China Ji Nan Jian Feng Chemical Co Ltd [Manufacturer]
  • Tel: 86-531-88110457
  • Fax: 86-531-88113608
  • Address: Hua Neng Road Ji Nan,ShandongChina

106266-06-2 RISPERIDONE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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106266-06-2 Risperidone

  • Risperidone, 99.93%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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References of 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,
7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Title: Risperidone
CAS Registry Number: 106266-06-2
CAS Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Manufacturers' Codes: R-64766
Trademarks: Belivon (Organon); Risperdal (J & J)
Molecular Formula: C23H27FN4O2
Molecular Weight: 410.48
Percent Composition: C 67.30%, H 6.63%, F 4.63%, N 13.65%, O 7.80%
Literature References: Combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Prepn: L. E. J. Kennis, J. Vandenberk, EP 196132; eidem, US 4804663 (1986, 1989 both to Janssen). Pharmacology: P. A. J. Janssen et al., J. Pharmacol. Exp. Ther. 244, 685 (1988). Receptor binding studies: J. E. Leysen et al., ibid. 247, 661 (1988). HPLC determn in plasma: A. Avenoso et al., J. Chromatogr. B 746, 173 (2000). Clinical study in psychoses: Y. G. Gelders et al., Pharmacopsychiatry 23, 206 (1990); in autism: L. Scahill et al., N. Engl. J. Med. 347, 314 (2002). Brief review: M. G. Livingston, Lancet 343, 457-460 (1994). Review of pharmacology and therapeutic potential: S. Grant, A. Fitton, Drugs 48, 253-273 (1994); B. Green, Curr. Med. Res. Opin. 16, 57-65 (2000); of clinical experience in schizophrenia: H.-J. M?ller, Expert Opin. Pharmacother. 6, 803-818 (2005),
Properties: Crystals from DMF + 2-propanol, mp 170.0°. LD50 in male, female mice, rats, dogs (mg/kg): 29.7, 26.9, 34.3, 35.4, 14.1, 18.3 i.v.; 82.1, 63.1, 113, 56.6, 18.3, 18.3 orally (Janssen, 1988).
Melting point: mp 170.0°
Toxicity data: LD50 in male, female mice, rats, dogs (mg/kg): 29.7, 26.9, 34.3, 35.4, 14.1, 18.3 i.v.; 82.1, 63.1, 113, 56.6, 18.3, 18.3 orally (Janssen, 1988)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Benzisoxazoles; Serotonin-Dopamine Antagonist.