Home > Name List By 7 > 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4- oxoquinoline-3-carboxylic acid China

CAS No 105956-97-6 , 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-
oxoquinoline-3-carboxylic acid Search by region : China

  • Name: 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-
    oxoquinoline-3-carboxylic acid
  • Synonyms: 105956-97-6; Clinafloxacin [INN]; CI-960;7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-
    oxoquinoline-3-carboxylic acid;
  • CAS Registry Number:
  • Melting Point: 253-258 C
  • Density: 1.573 g/cm3
  • Refractive index: 1.684
  • Safety Statements: S26;S36;
  • Hazard Symbols: Xi
  • Molecular Weight: 365.786583
  • InchiKey: QGPKADBNRMWEQR-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16
    (23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25)
  • Risk Statements: 36/37/38
  • Molecular Formula: C17H17ClFN3O3
  • Molecular Structure:CAS No:105956-97-6 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-<br />oxoquinoline-3-carboxylic acid

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References of 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-
oxoquinoline-3-carboxylic acid
Title: Clinafloxacin
CAS Registry Number: 105956-97-6
CAS Name: 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Molecular Formula: C17H17ClFN3O3
Molecular Weight: 365.79
Percent Composition: C 55.82%, H 4.68%, Cl 9.69%, F 5.19%, N 11.49%, O 13.12%
Literature References: Fluorinated quinolone antibacterial. Prepn: S. Suzue et al., EP 195316 (1986 to Kyorin). Antibacterial spectrum: M. S. Barrett et al., Diagn. Microbiol. Infect. Dis. 14, 389 (1991); S. M. H. Qadri et al., Chemotherapy (Basel) 38, 92 (1992).
Properties: Milk-white powder from chloroform-methanol-conc. aq. ammonia, mp 253-258° (dec).
Melting point: mp 253-258° (dec)
 
Derivative Type: Hydrochloride
CAS Registry Number: 105956-99-8
Manufacturers' Codes: AM-1091; CI-960; PD-127391
Molecular Formula: C17H17ClFN3O3.HCl
Molecular Weight: 402.25
Percent Composition: C 50.76%, H 4.51%, Cl 17.63%, F 4.72%, N 10.45%, O 11.93%
Properties: Light yellow prisms from methanol, mp 263-265° (dec).
Melting point: mp 263-265° (dec)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.