Home > Name List By 1 > 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-

CAS No 105219-56-5 , 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-

  • Name: 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-
  • Synonyms: 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-; WEB-2086; Apafanto;Apafant; WEB 2086BS; Apafantum [INN-Latin]; Apafantum; Apafanto [INN-Spanish]; Web 2086; triazolodiazepine;
  • CAS Registry Number:
  • Flash Point: 389.4°C
  • Boiling Point: 720.2°Cat760mmHg
  • Density: 1.48
  • Refractive index: 1.733
  • Flash Point: 389.4°C
  • Molecular Weight: 455.96038
  • InchiKey: JGPJQFOROWSRRS-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-
    12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,
    1H3
  • Molecular Formula: C22H22ClN5O2S
  • Molecular Structure:CAS No:105219-56-5 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-

Related products

Search by region :

Select to

105219-56-5 WEB 2086; 4-[3-[4[(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4 ]TRIAZOLO[4,3-A]DIAZEPIN-2-YL]-1-OXOPROPYL]MORPHOLINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

105219-56-5 APAFANT

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

105219-56-5 WEB 2086

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
Contact Supplier

105219-56-5 SC-201007 WEB-2086

  • United States Santa Cruz Biotechnology, Inc. [Manufacturer]
  • Tel: 831-457-3800/ 800-457-3801
  • Fax: 831-457-3801
  • Address: Santa Cruz Biotechnology, Inc.
    2145 Delaware Ave.
    Santa Cruz, CA 95060 null,nullUnited States
Contact Supplier

105219-56-5 WEB 2086

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
Contact Supplier

105219-56-5 APAFANT

  • China HANGZHOU ONICON CHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-571-85054016/ +86-571-85104679
  • Fax: +86-571-85054082
  • Address: HANGZHOU ONICON CHEMICAL CO.,LTD
    303-306 Hangzhou yiyao Building,
    No.439 Zhongshan North Rd.
    Hangzhou China
    Phone : +86-571-85054016
    Fax: +86-571-85054082
    E-Mail1: cjw9999@163.com null,nullChina
Contact Supplier

Select to

1/1
References of 1-Propanone,3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-
Title: Apafant
CAS Registry Number: 105219-56-5
CAS Name: 4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]morpholine
Synonyms: 3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone
Manufacturers' Codes: WEB-2086
Molecular Formula: C22H22ClN5O2S
Molecular Weight: 455.96
Percent Composition: C 57.95%, H 4.86%, Cl 7.78%, N 15.36%, O 7.02%, S 7.03%
Literature References: Platelet activating factor (PAF) antagonist. Prepn: K. H. Weber et al, DE 3502392; eidem, US 5082839 (1986, 1992 both to Boehringer, Ing.). Pharmacology: J. Casals-Stenzel et al., J. Pharmacol. Exp. Ther. 241, 974 (1987). Clinical pharmacology, pharmacokinetics: H. M. Brecht et al., Arzneim.-Forsch. 41, 51 (1991). Clinical effect vs PAF-induced bronchoconstriction: W. S. Adamus et al., Clin. Pharmacol. Ther. 47, 456 (1990).
Properties: Viscous, almost colorless oil. LD50 in mice (mg/kg): 540 i.v.; 4600 orally (Casals-Stenzel).
Toxicity data: LD50 in mice (mg/kg): 540 i.v.; 4600 orally (Casals-Stenzel)
Use: Tool to evaluate the role of PAF in exptl models of human disease.