CAS No:912545-86-9 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-<br />1-benzothiophene-2-carboxamide

3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide

CAS No.: 912545-86-9
Purity: 98%
Price: USD 250~1500/Kilograms
Weight: 490.05942
Place of Orign: wuhan,Hubei,China

Contact:Ms.Luna Wang

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Wuhan Sun-shine chemical Corporation Limited
China
Contact:Ms.Luna Wang
Tel:86--18312560332
Total Annual Sales Volume:US$1 Million - US$2.5 Million
Number of Employees:11 - 50 People
Business Type:Manufacturer,Trading Company
Main Markets:North America,Mid East,South America,Africa,Eastern Asia,Eastern Europe,Western Europe

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Product Name.:3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide
CAS No: 912545-86-9
Weight: 490.05942
Formula: C₂₈H₂₈ClN₃OS

Details

SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopamine action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). Induces pathway activation independently of Ptch proteins.

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3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide

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Zosuquidar(3HCl)

2,3-dimethyl-2,5-cyclohexadiene-1,4 dione

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