Home > Name List By 3 > 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide

CAS No 912545-86-9 , 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-
1-benzothiophene-2-carboxamide

  • Name: 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-
    1-benzothiophene-2-carboxamide
  • Synonyms: AC1NR49D; SureCN10029769;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-
    1-benzothiophene-2-carboxamide; SureCN14707297;CHEMBL2160033; SureCN8437026;
  • CAS Registry Number:
  • Molecular Weight: 490.05942
  • InchiKey: VFSUUTYAEQOIMW-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H28ClN3OS/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-
    2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20/h2-8,13-17,
    22-23,30H,9-12,18H2,1H3
  • Molecular Formula: C28H28ClN3OS
  • Molecular Structure:CAS No:912545-86-9 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-<br />1-benzothiophene-2-carboxamide

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912545-86-9 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide

  • SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopamine action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). Induces pathway activation independently of ...
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