beta-Sitosterol
Name: 24-Ethylcholest-5-en-3beta-ol,alpha-Dihydrofucosterol,22,23-Dihydrostigmasterol,24beta-Ethylcholesterol,5-Stigmasten-3beta-ol
EINECS: 201-480-6
Molecular Formula: C29H50O
CAS Registry Number: 83-46-5
Appearance: white solid
Molecular Weight: 414.71
Density: 0.97 g/cm3
Boiling Point: 501.9 oC at 760 mmHg
Melting Point: 139-142℃
Flash Point: 220.4 oC
Alpha: -28 o (C=2, CHCL3)
Storage Temperature: 20°C
Refractive index: 1.521
β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. Sitosterols are white, waxy powders with a characteristic odor. They are hydrophobic and soluble in alcohols.
The use of sitosterol as a chemical intermediate was for many years limited due to the lack of a chemical point of attack on the side-chain that would permit its removal. Extensive efforts on the part of many laboratories eventually led to the discovery of a pseudomonas microbe that efficiently effected that transformation. Fermentation digests the entire aliphatic side-chain at carbon 17 to afford a mixture of 17-keto products including dehydroepiandrosterone.
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