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Leflunomide

  • CAS No.: 75706-12-6
  • Purity: 98%
  • Min quantity: 500 Metric Tons
  • Price: USD 0.5~1/Kilograms
  • Place of Orign: Wuhan,Hubei,China
Ms.Debbie Yu

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Item specifics

  • Product Name.:Leflunomide
  • CAS No: 75706-12-6
  • Weight: 270.20727
  • Formula: C12H9F3N2O2
  • Melting Point: 163-168 ºC
  • Boiling Point: 289.3 °C at 760 mmHg
  • Density: 1.392 g/cm3

Details

Product Name: Leflunomide
Synonyms: LEFLUNOMIDE;HWA 486;ALPHA,ALPHA,ALPHA-TRIFLUORO-5-METHYL-4-ISOXAZOLECARBOXY-P-TOLUIDIDE;5-METHYLISOXAZOLE-4-(4-TRIFLUOROMETHYLCARBOXANILIDE);5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-4-ISOXAZOLECARBOXAMIDE;N-(4-TRIFLUOROMETHYLPHENYL)-5-METHYLISOXAZOL-4-CARBOXAMIDE;5-methylisoxazole-4-carboxylicacid(4-trifluoromethyl)anilide;5-methyl-n-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamid
CAS: 75706-12-6
MF: C12H9F3N2O2
MW: 270.21
Product Categories: Active Pharmaceutical Ingredients;API;Osteoarthritis and Rheumatoid Arthritis;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Aromatics;Heterocycles;An immunosuppressive agent;CARDENE;Other APIs
mp 163-168°C
storage temp. 2-8°C

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Chemical Properties Off White Crystalline Solid
Usage An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutical
Usage vasodilator
Usage anti-Altzheimer therapeutic.
Leflunomide

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