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5-Fluoroorotic acid

  • CAS No.: 703-95-7
  • Weight: 174.086723
  • Formula: C5H3FN2O4
  • Melting Point: 268 - 278 C
  • Place of Orign: zhuzhou,,China
Ms.sadiya sadiyal

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Item specifics

  • Product Name.:5-Fluoroorotic acid
  • CAS No: 703-95-7
  • Weight: 174.086723
  • Formula: C5H3FN2O4
  • Melting Point: 268 - 278 C
  • Density: 1.81 g/cm3

Details

Quick Details

ProName: 5-Fluoroorotic acid, monohydrate
CasNo: 703-95-7
Molecular Formula: C5H3FN2O4
Appearance: white crystalline powder
Application: for synthesis use
DeliveryTime: prompt
PackAge: as per buyers
Port: shanghai
ProductionCapacity: 10 Metric Ton/Month
Purity: 99%
Storage: Room temperature
Transportation: by air/sea
LimitNum: 1 Kilogram
Heavy metal: N/A

Uses:?

5-foa has become a valuable tool for research in the field of molecular genetics. it has been employed in the selection of resistant strains of saccharomyces cerevisiae that possess a mutant ura3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-foa is coverted to 5-fluorouridine monophosphate (5-fump) in yeast cells, which can become incorporated into rna or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-fdump). 5-fdump is a potent inhibitor of thymidylate synthase (ts), causing the cessation of dna synthesis. more recently, 5-foa has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroquine-resistant clones of plasmodium falciparum. studies indicate that ts is the primary target of 5-foa in malarial parasites. the combination of 5-foa and uracil has been effective in treating mice infected with plasmodium yoelli. 5-foa may also have potential in the treatment of human malarial infections when used in combination with other agents.??

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Superiority


★.best quality according to requirement
★.competitive price in china market
★.mature technical support
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contact information:


email:sadiya@yuanchengtech.com TEL:18873303856
QQ:2355326994
5-Fluoroorotic acid

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