CAS No:54965-24-1 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,<br />N-dimethylethanamine

Tamoxifen Citrate (Tamoxifen ,Nolvadex,Zitazonium, ICI-46474, TAM)

CAS No.: 54965-24-1
Min quantity: 1400 Kilograms
Weight: 563.63808
Formula: C₃₂H₃₇NO₈
Place of Orign: Zhuzhou,Hunan,China

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Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.
China
Contact:Mr.
Tel:86-731-22290217
Total Annual Sales Volume:US$5 Million - US$10 Million
Number of Employees:11 - 50 People
Business Type:Manufacturer
Main Markets:North America,Southeast Asia,Mid East,South America,Africa,Eastern Asia,Eastern Europe,Oceania,Western Europe

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Item specifics

Product Name.:Tamoxifen Citrate (Tamoxifen ,Nolvadex,Zitazonium, ICI-46474, TAM)
CAS No: 54965-24-1
Weight: 563.63808
Formula: C₃₂H₃₇NO₈
Melting Point: 140-144 ºC
Boiling Point: 665.9 °C at 760 mmHg

Details

Antiesdrogen Powder In High Quality Tamoxifen Citrate(Nolvadex, Zitazonium, ICI-46474, TAM)

Chemical Name: (Z)-2-[4-(1, 2-Diphenyl-1-butenyl)phenoxyl]-N, N-dimethyl-ethanamine-citrate;
1-p-beta-Dimethylaminoethoxyphenyl-trans-1, 2-diphenylbut-1-ene citrate

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Product name Tamoxifen citrate (Nolvadex)
Appearance White crystalline powder
Identification IR, UV conform Conform
Loss on drying ≤ 0.5ml 0.21ml
Residue on ignition Not more than 0.2% 0.06ml
Iron Not more than 0.005% 0.0018%
Heavy metals Not more than 0.001% 0.0006%
Related substances Total: Not more than 1.0%
Individual: Not more than 0.5% 0.32%
0.14%
E-isomer Not more than 0.3% 0.19%
Organic volatile impurities Conforms Conforms
Assay 99.0~101.0% 99.51%

How It Works
Tamoxifen is the most commonly used hormone therapy for the treatment of breast cancer.

Many women have breast cancer that tests positive for estrogen receptors (ER+). This means that estrogen promotes the growth of the breast cancer cells. Tamoxifen blocks the effects of estrogen on these cells. It is often called an "anti-estrogen."

How Well It Works
Tamoxifen is highly effective in lowering the risk of breast cancer recurrence. In women who have already had breast cancer, tamoxifen also lowers the risk of breast cancer in the opposite breast (contralateral).

For postmenopausal women, a two-stage treatment using tamoxifen and then an aromatase inhibitor, such as anastrozole (Arimidex), exemestane (Aromasin), or letrozole (Femara) may work better than only taking tamoxifen.

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