MedChemexpress(MCE)provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use. MCE has an enthusiastic, energetic and friendly Technical and Customer Support team with years of experience in the Life Science industry. MCE lay great attention on the purity, stability and activity of the compounds, esp. You can rely on us to be a com...
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Description: THZ1 THZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50(binding affinity) of 3.2 nM; inhibits Jurkat cell's proliferation with IC50 of 50 nM. IC50 value: 3.2 nM (Kd for CDK7)[1] Target: CDK7 THZ1 has the unprecedented ability to t...
Description: (+)-JQ-1 (+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2). IC50 Value: 77 nM(for BRD4(1)); 33 nM( for BRD4(2)) Target: BRD4 in vitro: (+)-JQ1 enantiomer binds directly into the Kac binding site of BET bromodomains. Targe...