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CAS No:1268524-70-4 (S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
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(+)-JQ-1

  • CAS No.: 1268524-70-4
  • Purity: >98%
  • Weight: 456.9882
  • Formula: C23H25ClN4O2S
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:(+)-JQ-1
  • CAS No: 1268524-70-4
  • Weight: 456.9882
  • Formula: C23H25ClN4O2S
  • Boiling Point: 610.4±65.0 °C at 760 mmHg
  • Density: 1.33

Details

(+)-JQ-1(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2).

IC50 Value: 77 nM(for BRD4(1)); 33 nM( for BRD4(2))

Target: BRD4

in vitro: (+)-JQ1 enantiomer binds directly into the Kac binding site of BET bromodomains.

Target:Estrogen Receptor_ERR

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CAS No:1268524-70-4 (S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

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