100% Natural Green Coffee Bean Extract 50% Chlorogenic Acid
Description Of Green Coffee Bean Extract Chlorogenic Acid
Product Name:Green Coffee Bean Extract Chlorogenic Acid
Supplier: Hunan World Well-being BioTech Co.,Ltd
Part of used: Seed
Test Method: HPLC
Active ingredient: Chlorogenic acids
Family:Rubiaceae
Function:Weight loss,Anti-oxidation,Anti-agin
Specs Available:50% 60%
Latin name:Coffea Arabica L.
Appearance:Brown fine powder
CAS NO.:327-97-9
Main Function Of Green Coffee Bean Powder Chlorogenic Acid
1.Green Coffee Bean Powder Chlorogenic acid, long known as an antioxidant with potential
anti-cancer activity, also slows the release of glucose into bloodstream after a meal.
2.Green Coffee Bean Powder Chlorogenic Acid can lower one’sblood sugar level, suppress the appetite, lower blood pressure, and reduce levels of visceral fat.
3.Green Coffee Bean Powder Chlorogenic Acid Useful in fighting the free radicals in our bodies that can damage our cells and contribute to conditions such as cardiovascular disease.
4.Green Coffee Bean Powder Chlorogenic Acid Act as an effective painkiller especially for migraine medications;
5.Green Coffee Bean Powder Chlorogenic Acid Reduce the risk of diabetes;
6.Green Coffee Bean Powder Chlorogenic Acid Assist the body to burn at higher proportion of lipids-fats compared to carbohydrates
Applications Of Green Coffee Bean Powder Chlorogenic Acid
1.Green Coffee Bean Powder Chlorogenic Acid are appliedin functional food additive & health supplement
2.Green Coffee Bean Powder Chlorogenic Acid are appliedin Beverage
3.Green Coffee Bean Powder Chlorogenic Acid are applied in Cosmetics & personal care products.
Usage Of Green Coffee Bean Powder Chlorogenic Acid
Chlorogenic acid, long known as an antioxidant with potential anti-cancer activity, also slows the release of glucose into bloodstream after a meal.
· lower one’sblood sugar level, suppress the appetite, lower blood pressure, and reduce levels of visceral fat.
· useful in fighting the free radicals in our bodies that can damage our cells and contribute o conditions such as cardiovascular disease.Test results showed Green Coffee Bean had more than double the rate of oxygen radical absorbance capability when compared to green tea and grape seed extracts.
· Act as an effective painkiller especially for migraine medications;
· Reduce the risk of diabetes;
· Assist the body to burn at higher proportion of lipids-fats compared to carbohydrates, which could help with muscle fatigue for athletes and bodybuilders.So it is great for sports formulations
· Chlorogenic Acid have biological effects in the small intestine that alter patterns of glucose uptake, helping to regulate the metabolism.
Health Benefits of Green Coffee Bean Extract Chlorogenic Acid
1. Anti oxidative effects of Green Coffee Bean Extract Chlorogenic Acid
In the investigation of the impact of consumption of a coffee containing high levels of chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally,other redox biomarkers were monitored in an intervention trial, found that the oxidation of DNA, lipids and proteins associated with the incidence of various diseases and the protection against their oxidative damage may be indicative for beneficial health effects of coffee.
2. Hepatoprotective effects of Green Coffee Bean Extract Chlorogenic Acid
In the investigation of the potential protective effects of chlorogenic acid (CGA) on acute liver injury caused by lipopolysaccharide (LPS) in mice, found that CGA also decreased the elevated plasma levels of ALT and AST. At the transcriptional level, CGA pretreatment suppressed hepatic mRNA expression of toll-like receptor 4 (TLR4), TNF-alpha and NF-kappaB p65 subunit. In contrast, mRNA level of the transcriptional coactivator PGC-1alpha was restored by CGA. Finally, CGA reduced the phosphorylation of NF-kappaB p65 subunit in the liver.
3. Anti-obesity of Green Coffee Bean Extract Chlorogenic Acid
in the investigation of the efficacy of chlorogenic acid on altering body fat in high-fat diet(37% calories from fat) induced-obese mice compared to caffeic acid. Caffeic acid or chlorogenic acid was supplemented with high-fat diet at 0.02% (wt/wt) dose, found that Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated receptors alpha expression in the liver compared to the high-fat group, and concluded that
caffeic acid and chlorogenic acid improve body weight, lipid metabolism and obesity-related hormones levels in high-fat fed mice. Chlorogenic acid seemed to be more potent for body weight reduction and regulation of lipid metabolism than caffeic acid.
4. Anti-inflammatory effects of Green Coffee Bean Extract Chlorogenic Acid
In the assessment in vivo of the anti-inflammatory and antinociceptive activities of the aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina,Scorzonera cana var. jacquiniana, Scorzonera cana var. radicosa, Scorzonera cinerea,Scorzonera eriophora, Scorzonera incisa, Scorzonera laciniata ssp. laciniata, Scorzonera parviflora and Scorzonera sublanata and theirs effect against inflammation and to relieve pain, found that Scorzonera cana var. jacquiniana, Scorzonera cinerea, Scorzonera eriophora,
Scorzonera incisa and Scorzonera parviflora possess significant anti-inflammatory and
antinociceptive activity. It has been suggested that flavonoids and chlorogenic acid are partly responsible for mentioned activities of Scorzonera species.
5. Antioxidants of Green Coffee Bean Extract Chlorogenic Acid
In the study of the chemical composition and the antioxidant activity of spent coffee grounds and coffee husks extracts, obtained by supercritical fluid extraction (SFE) with
CO(2) and with CO(2) and co-solvent, found that the best antioxidant activity was showed by coffee husk extracts obtained by LPE. The quantification and the identification of the extracts were accomplished using HPLC analysis. The main compounds identified were caffeine and chlorogenic acid for the supercritical extracts from coffee husks.
6. Antitussive of Green Coffee Bean Extract Chlorogenic Acid
In the investigation of the orally administrated the water extracts in mice. Ammonia induced mice coughing model was used to evaluate the antitussive activity, found that only flower bud can be used as the antitussive and expectorant herbal drug. The high concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds may be related with the antitussive and expectorant effects of Flos Farfara. To guarantee the clinical effect, rachis should be picked out before use.
7. Rheumatoid Arthritis of Green Coffee Bean Extract Chlorogenic Acid
In the investigation the antiarthritic activities of this compound in adjuvant induced-arthritis in male Wistar rats, and exploration of the underlying mechanisms of actions in view of immunological responses, found that CGA efficiently suppressed CD80/86 but failed to bring any changes in the CD28 count, whereas ibuprofen (standard drug) resulted in highly significant inhibition of both. We next examined the effect on CD4(+) T cells specific Th1/
Th2 cytokines by flow cytometry and observed that CGA suppressed the Th1 cytokines in a highly significant manner but elevated Th2 cytokines with dose dependence. Results of the present investigation suggest that CGA is a potent antiarthritic agent.
Cherry Chan
Tel:13501541862
Skype: qiurongchan
worldwellbeing02(at)gmail.com
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