Flibanserin
Synonyms: Flibanserin;Bimt 17;3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one;Filbanserin;Flibanerins
CAS: 167933-07-5
MF: C20H21F3N4O
MW: 390.4
Appearance: White powder
Grade: Pharmaceutical grade
Usage: Adrug being studied as a non-hormonal treatment for pre-menopausal women with hypoactive sexual desire disorder (HSDD).
Applications: A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials. The Food and Drug Administration posted the clinical trial results on its website today in advance of a committee meeting on Friday, when a panel of experts will vote whether or not to recommend approval of the drug called flibanserin. (The FDA usually follows the recommendations of its expert panels. ) Although there was a slight increase in the number of sexually satisfying events flibanserin users had each month, the FDA staff who reviewed the results said the so-called response rate isn't "particularly compelling. "
It's called the "little pink pill, " a tiny tablet that could have a huge impact on treating female sexual dysfunction. If it's approved, it would become the first drug of its kind on the market.
Packing:foil bag or as required
Items Specification
Appearance white crystals or crystalline powder, has a faint, characteristic odor and bitter taste
Solubility freely soluble in water and 95%ethanol, sparingly soluble in acetic anhydride and practically insoluble in diethyl ether
pH 3.5-4.5
Identification 1, red to dark purple color appears with(III)iron chloride
2, light red precipitate formed with reinecke salt TS
3, UV spectrum meet the reference
4, solution (1%) responds to the qualitative test for chloride
Melting point 139-143 celcius degree
Clarity and color of solution clear and colorless
Sulfate 0.048%max
Heavy metals 10ppm max
As 2ppm max
Organic acid(0.1M NaOH) 0.54ml max
Loss on drying 0.5% max
Residue on ignition 0.1%max
Residual organic Solvents (GC) Xylol 0.217%max
Isopropanol 0.5%max
Related substances(HPLC) Total impurity 1.5%max
Single impurity0.5%max
Free P-chloro phenoxy acetic 0.5%max
Count of bacteria bacillus 1000/1g max
Mildew 100/1g max
Microzyme 100/1g max
Assay(C12H16CINO3.HCl,on dry basis) 98%min
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Testolactone CAS:968-93-4
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Medroxyprogesterone Acetate CAS: 71-58-9
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