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Flibanserin Hydrochloride

  • CAS No.: 147359-76-0
  • Purity: 99%min
  • Min quantity: 100 Kilograms
  • Place of Orign: Hengyang,Hunan,China
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Item specifics

  • Product Name.:Flibanserin Hydrochloride
  • CAS No: 147359-76-0
  • Formula: C20H21 F3 N4 O . Cl H

Details

Description:

Flibanserin is a medication for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three.


Applications:

Flibansetrin has high affinity for serotonin receptors in the brain: it acts as an agonist on 5-HT1A and an antagonist on 5-HT2A. In vivo, flibanserin binds equally to 5-HT1A and 5-HT2A receptors. However, under higher levels of brain 5-HT (i.e., under stress), flibanserin may occupy 5-HT2A receptors in higher proportion than 5-HT(1A) receptors. It may also moderately antagonize D4 (dopamine) receptors and 5-HT2B and 5-HTB2C. Its action on neurotransmitter receptors may contribute to reduction in serotonin levels and increase in dopamine and norepinephrine levels, all of which may play part in reward processing.
Flibanserin Hydrochloride

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