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AMG-925

  • Purity: 98%
  • Price: USD 260~2000/Kilograms
  • Place of Orign: wuhan,Hubei,China
Ms.Luna Wang

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  • Product Name.:AMG-925
  • CAS No: 1401033-86-0

Details

AMG-925 is a potent and orally bioavailable dual inhibitor of CDK4 and FLT3, including many FLT3 mutants reported to date. It inhibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb(+)) and U937 (FLT3(WT)) and induced cell death in MOLM13 (FLT3(ITD)) and even in MOLM13 (FLT3(ITD, D835Y)), which exhibits resistance to a number of FLT3 inhibitors currently under clinical development.

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AMG-319

CAS No: 1608125-21-8

Purity: 98%

Min quantity: null null

Price: 280 ~ 1100 USD

Description: AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor c...

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