Effective Femara Anti Estrogen Steroids Letrozole Raw Powders for Cancer Treatment CAS 112809-51-5
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Quick Detail:
Letrozole (Femara)
CAS: 112809-51-5
Assay: 98.0-102.0%. USP32
Packing: 1Kg/foil bag
Delivery: Courier.
MF: C17H11N5
MW: 285.3
MP: 181-183 degrees
Character: White crystalline powder.
Description:
Femara(generic name is letrozole) is a new drug developed for the treatment of advanced breast cancer in women. Femara is the second in a new class of third-generation selective oral aromatase inhibitors.
It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen. Since many forms of breast cancer cells are stimulated by estrogen, it is hoped that by reducing amounts of estrogen in the body the progression of such a disease can be halted. This is the basic premise behind Nolvadex, except this drug blocks the action and not production of estrogen.
The effects of Femara can be quite dramatic to say the least. A daily dose of one tablet (2.5 mg) can produce estrogen suppression greater than 80 % in treated patients. With the powerful effect this drug has on hormone levels, it is only to be used (clinically) by post-menopausal women whose disease has progressed following treatment with Nolvadex. Side effects like hot flushes and hair thinning can be present, and would no doubt be much more severe in pre-menopausal patients.
With the one drug halting estrogen conversion and the other blocking 5-alpha reduction (testosterone, methyltestosterone and Halotestin only), related side effects can be effectively minimized. Here the strong androgen testosterone could theoretically provide incredible muscular growth, while at the same time being as tolerable as nandrolone.
Additionally the quality of the muscle should be greater, the athlete appearing harder and much more defined without holding excess water.
Applications:
1. Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer.
2. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia.
3. It will also raise testosterone levels because of the lowered estrogen in the body.
4. Femara(generic name is letrozole) is a new drug developed for the treatment of advanced breast cancer in women.
5. Femara is the second in a new class of third-generation selective oral aromatase inhibitors.
6. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.
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COA:
Tests
Specifications
Results
Appearance
White or off-white crystaline powder
White
Crystalline powder
Solubility
Soluble in Chloroform;
Soluble in ethanol when heated
Conform
ldentification
(1)Maximum absorption in wavelength of 240 nm
Minimum absorption in wavelength of 215 nm
Conform
Conform
(2)Infrared spectrum should be in accordance
the dominant peak of contrast
In accordance with the dominant
peak of contrast
Melting points
182°C-184°C
182°C
Related substances
≤0.5%
0.3%
Single impurity
≤0.3%
0.2%
Loss on drying
≤1.0%
0.8%
[Assay]C17H11N5
(On anhydrous basis)
≥98.0%
99.2%
Conclusion
Conforms Specifications of USP35
Specifications:
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