MedChemexpress(MCE)provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use. MCE has an enthusiastic, energetic and friendly Technical and Customer Support team with years of experience in the Life Science industry. MCE lay great attention on the purity, stability and activity of the compounds, esp. You can rely on us to be a com...
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Description: MLN4924 MLN4924 is a potent and selective small molecule NEDD8-activating enzyme (NAE) inhibitor (IC50 = 4.7 nM). IC50 value: 4.7 nM Target: NAE At much higher concentrations, MLN 4924 inhibits the related enzymes ubiquitin-activating enzyme (UAE) an...
Description: MLN120B MLN120B is a potent and effective IKKbeta inhibitor. IC50 Value: MLN120B (20 umol/L) induced up to 35% and 75% inhibition, assessed by MTT assay and [3H]thymidine uptakein multiple myeloma cell lines, respectively. Target: IKKbeta NF-κB path...