基本信息
DIAD
【中文名称】偶氮二甲酸二异丙酯
【英文名称】diisopropyl azodiformate;DIPA
缩写：DIAD 结构式：
CAS：2446-83-5
外观：桔红色透明油状液体
含量>98%（GC）
包装：25KG/桶 200KG/桶
溶解情况
溶于一般增塑剂，与塑料互溶性好。
其他
热稳定性好。贮存稳定。分解物无色、无毒、不污染、不喷雾、无臭味。在40～120℃范围内可获得高发气量。
中文名称： 偶氮二甲酸二异丙酯
二异丙基偶氮羟酸盐
英文名称： diisopropyl azodicarboxylate
Cas号 【2446-83-5】
MDL号: --MFCD00008875
Beilstein 号 1912326
EINECS: --219-502-8
分子式 C8H14N2O4；(CH3)2CHOOCN=NCOOCH(CH3)2
分子量 202.21
别名 DIAD
Azodicarboxylic Acid Diisopropyl Ester
密度:1.02
熔点:3-5℃
沸点:75℃ (0.2 mmHg)
折光率nD20:1.418-1.422
闪点:106℃
用途： 医药中间体，有机合成试剂，橡胶塑料液体发泡剂。
性状: 桔红色透明油状液体，有特殊气味。溶于一般增塑剂，与塑料互溶性好，热稳定性好。贮存稳定。分解物无色、无毒、不污染、不喷霜、无臭味。
英语原文
==================MSDS===================
Material Safety Data Sheet
Diisopropyl azodicarboxylate
Section 1 - Chemical Product and Company Identification
MSDS Name: Diisopropyl azodicarboxylate
Synonyms: DIAD
Company Identification: shanghai aladdin reagent co.,Ltd
For information in China, call: 021 -38953866
Emergency Number, China: 021 -38953839
Section 2 - Composition, Information on Ingredients
CAS# Chemical Name: % EINECS#
2446-83-5 Diisopropyl azodicarboxylate 94% 219-502-8
Hazard Symbols: XI N
Risk Phrases: 36/37/38 51/53
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation.
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled.
Chronic: Prolonged or repeated skin contact may cause dermatitis.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Exposure to heat may promote violent decomposition. Violently decomposes when heated under confinement. Containers may explode if exposed to fire. Risk of explosion if heated under confinement.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use a spark-proof tool. Do not let this chemical enter the environment.
Section 7 - Handling and Storage
Handling: Contents may develop pressure upon prolonged storage. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light. Use and store under nitrogen. Keep away from heat, sparks and flame. Keep away from heat and flame. Material is heat sensitive.
Storage: Keep away from heat and flame. Do not store in direct sunlight. Store in a tightly closed container. Store in a dry area. Keep refrigerated. (Store below 4°C/39°F.) Heat can cause thermal decomposition and pressure build-up inside containers.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits
CAS# 2446-83-5:
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Clear liquid
Color: orange
Odor: pungent odor
pH: Not available
Vapor Pressure: 1.04hPa @20 deg C
Viscosity: Not available
Boiling Point: 75 deg C @0.2mmHg ( 167.00°F)
Freezing/Melting Point: 3 - 5 deg C
Autoignition Temperature: Not available
Flash Point: 106 deg C ( 222.80 deg F)
Explosion Limits: Lower: Not available
Explosion Limits: Upper: Not available
Decomposition Temperature: Not available
Solubility in water: Insoluble
Specific Gravity/Density: 1.020
Molecular Formula: C8H14N2O4
Molecular Weight: 202.21
Section 10 - Stability and Reactivity
Chemical Stability: Stable, however, temperatures above 100°C may lead to explosive decomposition. Light sensitive. Heat sensitive.
Conditions to Avoid: Incompatible materials, light, ignition sources, temperatures above 65°C, heating to decomposition.
Incompatibilities with Other Materials Strong oxidizing agents, strong bases, alcohols, Lewis acids, alkalies.
Hazardous Decomposition Products Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization Has not been reported.
Section 11 - Toxicological Information
RTECS#: CAS# 2446-83-5: None listed
LD50/LC50: RTECS: Not available. Other: dermal rabbit LD50 = 2150 mg/kg inh rat LC50 = 12000 mg/L/8H inh rat LC50 = 28.4 mg/L
Carcinogenicity: Diisopropyl azodicarboxylate - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other: The toxicological properties have not been fully investigated.
Section 12 - Ecological Information
Ecotoxicity: Fish: Cyprinus carpio: 13.4 mg/L; 96H; LC50
Fish: Cyprinus carpio: 18 mg/L; 96H; LC100
Daphnia: Daphnia: 42 mg/L; 48H; EC50
Daphnia: Daphnia: 32 mg/L; 48H; NOEC
Daphnia: Daphnia: 46 mg/L; 48H; EC100
Fish: Cyprinus carpio: 10 mg/L; 96H; LC0
Other: Not readily biodegradable.
Algae:Selenastrum capricornutumNOEC = 4.6 mg/L/72HEC50 = 6.8 mg/L/72HEC100 = 10 mg/L/72HBiodegradationModified Sturm testCO2 evolution test15% elimination in 28d
Section 13 - Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - Transport Information
IATA IMO RID/ADR
Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.* ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard Class: 9 9 9
UN Number: 3082 3082 3082
Packing Group: III III III
Section 15 - Regulatory Information
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI N
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 29 Do not empty into drains.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S 61 Avoid release to the environment. Refer to special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 2446-83-5: Not available
Canada
US Federal
TSCA
CAS# 2446-83-5 is not listed on the TSCA Inventory. It is for research and development use only.
Section 16 - Other Information
MSDS Creation Date: 1/12/1999
Revision #3 Date 5/25/2007
Revisions were made in Sections: 3, 9, 10, 11, 14
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the company has been advised of the possibility of such damages.
