GW501516

• Product NameGW501516
  CAS No.317318-70-0
  Purity98%
  Min Quantity500Kilograms
  Price1~1
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  Molecular Structure

Detailed Description

GW501516

Alias: 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid; GW1516; GW501516; GSK-516
CAS: 317318-70-0
Appearance:White Solid
M.F.: C21H18F3NO3S2
M.W.: 453.5
M.S.:

M.P.: 134-136°C
Usage:An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
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• GW501516