Tenofovir disoproxil fumarate, marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in human immunodeficiency virus 1 (HIV-1) and hepatitis B virus infections.
Application:
1.Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.[2] This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.
2.Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older
Specification:
Product Name:
Tenofovir [PMPA]
CAS NO.:
147127-20-6
MF:
C9H14N5O4P
MW:
287.2
Standard:
In-house. FDA;USDMF
Appearance:
White to off white powder
Status:
Commercial
Application:
Antivirus, Anti-HIV
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