Product name
Tetracaine HCl Factory Supplying
Other name
Tetracaine hydrochloride
CAS register number
136-47-0
EINECS
205-248-5
Molecular formula
C15H25ClN2O2
Molecular weight
300.82
Molecular structure
Powdered Anesthetic Pain Killer Drug / Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride
Melting point
149°C
Assay
99%
Product description:
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
COA and HPLC:
COA:
Product name
Tetracaine HCl
Appearance
White crystalline powder
Assay(*)
98~101.0%
100.4%
Identification
A.By UV, To match with working standard
Complies
B: Dissolve 100 mg in 10 mL of water, and add 1 mL of potassium thiocyanate
solution (1 in 4): a crystalline precipitate is formed. Recrystallize the precipitate
from water, and dry at 80 for 2 hours: it melts between 130 and 132 .
Complies
C. A solution of 100 mg in 5 mL of water meets the requirements of the
Tests for Chloride
Complies
PH
Chromatographic purity
Clarity
4.5~6.5
5.9
Conform to standard
Complies
Solution should be clear
Complies
Related Substances
Not more than the reference solution (0.05%)
Complies
Heavy metals
≤10ppm
<10ppm
Loss on drying
<0.5%
0.21%
Resiue on ignition
≤0.1%
0.05%
Melting range
145~150°C
146~149°C
For detail, please contact:
Dawn (miss)
Email: cherry@ycphar.com
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