Aprepitant
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![CAS No:170729-80-3 5-[[(2R,3S)-2-[(1R)-1-[3,<br />5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]<br />methyl]-1,2-dihydro-1,2,4-triazol-3-one](http://www.vvchem.com/structure/cas-170/170729-80-3.png)
Molecular Structure
Detailed Description
epitant, with CAS 170729-80-3, is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA).
Aprepitant (CAS 170729-80-3) is effective in helping to prevent CINV because it antagonizes the NK1 receptor. This receptor is located at the brain stem nuclei of the dorsal vagal complex and is a crucial part of the regulation of vomiting.
This is due to the receptor binding with substance P. Aprepitant (CAS 170729-80-3) can be used to treat acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.
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