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L-Glutathione reduced

  • CAS No:70-18-8 (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-<br />yl]amino]-5-oxopentanoic acid
    Molecular Structure

    Detailed Description

    Name: L-Glutathione reduced
    Synonyms: 5-L-Glutamyl-L-cysteinylglycine; gamma-L-Glutamyl-L-cysteinylglycine; GSH
    Molecular Formula: C10H17N3O6S
    Molecular Weight: 307.32
    CAS Registry Number: 70-18-8

    Appearance: White crystals or crystalline powder.
    State of solution: Clear and colorless
    Melting Point: About 185°C (with decomposition)
    Specific Rotation(α)D 20 : -15.5°to -17.5°
    Identification: Similar with the reference spectrum
    Assay: 98.0% to 101.0%
    Loss on drying: 0.50% max.
    Related substances: 2.0% max.
    Heavy metals (Pb): 10ppm max.
    Arsenic(As2O3): 2ppm max.
    Residue on ignition(sulfated): 0.10% max.

    Function:
    Reduced L-glutathione is a well-known tripeptide, -glutamyl-cysteinyl-glycine, abbreviated GSH. It is the most abundant low-molecular-weight thiol, and GSH/glutathione disulfide is the major redox couple in animal cells. "Glutathione deficiency contributes to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases (including kwashiorkor, seizure, Alzheimer's disease, Parkinson's disease, liver disease, cystic fibrosis, sickle cell anemia, HIV, AIDS, cancer, heart attack, stroke, and diabetes).