Wuhan Sun-shine chemical Corporation Limited

Wuhan Sun-shine chemical Corporation Limited

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  • Company Name: Wuhan Sun-shine chemical Corporation Limited
  • Street: No.388 Gaoxin Road (No.2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC.
  • City: WuHan
  • Province/state: Hubei
  • Country/region: China
  • Contact Person: Ms.Luna Wang
  • Tel: 86--18312560332
  • Fax: --
  • Email:

MT-DADMe-ImmA(MTDIA HCl)

  • Product NameMT-DADMe-ImmA(MTDIA HCl)
    CAS No.1399840-35-7
    Purity98%
    Min Quantity
    Price260~900
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    Detailed Description

    Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methylthioadenosine phosphorylase (MTAP). Treatment of cultured cells with MT-DADMe-ImmA and MTA inhibited MTAP, increased cellular MTA concentrations, decreased polyamines, and induced apoptosis in FaDu and Cal27, two head and neck squamous cell carcinoma cell lines.The selective action of MT-DADMe-ImmA on head and neck squamous cell carcinoma cells suggests potential as an agent for treatment of cancers sensitive to reduced CpG island methylation.