Vismodegib(GDC-0449)
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- Product NameVismodegib(GDC-0449)
- CAS No.314245-33-5
- Purity98%
- Min Quantity
- Price350~1000
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Detailed Description
IU1 is a reversible and specific inhibitor of proteasome-associating Usp14. It does not inhibit other deubiquitinating enzymes of the 26S proteasome. It partially inhibits the ubiquitin chain trimming activity of the 26S proteasome, which could function to stimulate the degradation of some proteasomal substrates.