Wuhan Sun-shine chemical Corporation Limited

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3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide

  • Product Name3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]- 1-benzothiophene-2-carboxamide
    CAS No.912545-86-9
    Purity98%
    Min Quantity
    Price250~1500
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  • CAS No:912545-86-9 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-<br />1-benzothiophene-2-carboxamide
    Molecular Structure

    Detailed Description

    SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopamine action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). Induces pathway activation independently of Ptch proteins.