Wuhan Sun-shine chemical Corporation Limited

Wuhan Sun-shine chemical Corporation Limited

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  • Company Name: Wuhan Sun-shine chemical Corporation Limited
  • Street: No.388 Gaoxin Road (No.2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC.
  • City: WuHan
  • Province/state: Hubei
  • Country/region: China
  • Contact Person: Ms.Luna Wang
  • Tel: 86--18312560332
  • Fax: --
  • Email:

Luminespib(NVP-AUY922)

  • CAS No:747412-49-3 (5Z)-N-ethyl-5-(4-hydroxy-6-oxo-3-propan-2-ylcyclohexa-2,<br />4-dien-1-ylidene)-4-[4-(morpholin-4-ylmethyl)phenyl]-2H-1,<br />2-oxazole-3-carboxamide
    Molecular Structure

    Detailed Description

    NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was discovered through a collaboration between The Institute of Cancer Research and the pharmaceutical company Vernalis and licensed to Novartis. It is currently in Phase II clinical trials. NVP-AUY922 is an inhibitor of heat shock protein 90 (Hsp90), which is a chaperone protein that plays a role in the modification of a variety of proteins that have been implicated in oncogenesis. NVP-AUY922 has shown promising activity in preclinical testing against several different tumor types.