XL-880,Foretinib
Detailed Description
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFR/ and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
- XL-880,Foretinib