Drospirenone

• Product NameDrospirenone
  CAS No.67392-87-4
  Purity99%
  Min Quantity8000Kilograms
  Price3~5
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  Molecular Structure

Detailed Description

Drospirenone
Alias: 6b,7b:15b,16b-Dimethylen-3-oxo-17a-pregn-4-ene-21,17-carbolactone; Dihydrospirorenone
CAS NO: 67392-87-4
Molecular formula: C24H30O3
Molecular weight: 366.49
Assay:99%
Purity :99%
EINECS No.: 266-679-2
Density: 1.26g/cm3
Melting point: 196-200 ℃
Boiling point: 552.2 ° C at 760 mmHg
Flash point: 241.6 ° C
Steam pressure: 3.07E-12mmHg at 25 ° C
alpha: -180° (c=0.5, chloroform)
InChI: InChI=1/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
Steam pressure: 3.07E-12mmHg at 25 ° C
Packing: Foil bag
Usage: Synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity.Drospirenone (Drospirenone) and its analogues, is a kind of high efficient, low toxicity, no side effects of a new generation of steroidal contraceptives, first by France Schering company in 2000 developed the fourth generation of oral contraceptives, anti mineralocorticoid and anti androgenic effects, and wide market prospect

Description:

Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.

It is sold under the brand names Yasmin, Yasminelle, Yaz, Beyaz, Ocella, Zarah, Daylette and Angeliq, all of which arecombination products of drospirenone with an estrogen such as ethinylestradiol or estradiol.

Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has potent antimineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and has also been shown to possess mild antiandrogen activity.

The antimineralocorticoid properties exhibited by drospirenone promote sodium excretion and prevent water retention.

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• Drospirenone