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![CAS No:57-91-0 (8R,9S,13S,14S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,<br />17-decahydrocyclopenta[a]phenanthrene-3,17-diol](http://www.vvchem.com/structure/cas-57/57-91-0.png)
Molecular Structure
Detailed Description
Estradiol
Other name:17α-estradiol
CAS: 57-91-0
EINECS: 200-023-8
Molecular formula: C18H24O2
Molecular weight: 272.38
Melting point: 176-180°C
Assay: 98%
Product description:
Estradiol is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it.
The menstrual cycle in women involves predictable variations in the levels of several hormones, with estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last for the full gestation period.
Usage: Estradiol (known as α-Estradiol or 17α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer's disease and ischemic stroke.
Biological Activity Endogenous estrogen receptor ligand
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- Estradiol service01@chembj.com
June
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