shanghai missyou chemical co.,ltd.

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  • Country/region: China
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  • CAS No:290297-26-6 2-[3,5-bis(trifluoromethyl)phenyl]-N,<br />2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]<br />propanamide
    Molecular Structure

    Detailed Description

    2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide Chemical Properties
    Melting point 156.2-160.0 °C
    Boiling point 597.4±50.0 °C(Predicted)
    density 1.255
    pka 7.89±0.38(Predicted)
    Safety Information
    MSDS Information
    2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide Usage And Synthesis
    Uses Antiemetic.
    Definition ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoic acid with the secondary amino group of N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin 3-amine; an antiemetic used in combination with palonosetron hydrochloride (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.