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4-methyl cinnamic acid methyl ester

  • CAS No:20754-20-5 methyl (E)-3-(4-methylphenyl)prop-2-enoate
    Molecular Structure

    Detailed Description

    Name: 4-methyl cinnamic acid methyl ester
    CAS No.: 20754-20-5
    Formula: C11H12O2
    Molecular Weight: 176.21
    Melting point: 58~62℃
    Boiling point: 273℃
    Density: 1.057g/cm3
    Flash point: 152℃
    Refractive index?: (20°C)1.5371
    Molar volume: (m3/mol)153.3
    Appearance: Color white to pale yellow crystalline powder
    Purity:>98%
    Package?specification:25 kg / cardboard drum
    Storage: Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.
    Usage:
    METHYL4-METHYLCINNAMATE is mainly used to synthesize methyl p-bromomethyl cinnamate as an upstream raw material for the antithrombotic drug Ozagrel Sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After alkaline condensation with the imidazole in the acid salt at room temperature, the antithrombotic drug ozagrel sodium was obtained with a total yield of 67%。