Valproic acid
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Molecular Structure
Detailed Description
Name:Valproic acid
Cas No:99-66-1
MF:C8H16O2
Use: anticonvulsant and mood-stabilizing
Appearance:white powder
Indications:
As an anticonvulsant, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, juvenile myoclonic epilepsy, and the seizures associated with Lennox-Gastaut syndrome. It is also used in treatment of myoclonus. In some countries, parenteral preparations of valproate are used also as second-line treatment of status epilepticus, as an alternative to phenytoin. Valproate is one of the most common drugs used to treat posttraumatic epilepsy.
Valproic acid is also FDA-approved for the treatment of manic episodes associated with bipolar disorder, adjunctive therapy in multiple seizure types (including epilepsy), and prophylaxis of migraine headaches. It is more recently being used to treat neuropathic pain, asAsecond line agent, particularly lancinating pain fromAdelt Afibers.