Formestane
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![CAS No:566-48-3 (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,<br />16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione](http://www.vvchem.com/structure/cas-566/566-48-3.png)
Molecular Structure
Detailed Description
Lentaron Anesthetic Anodyne 566-48-3 Formestane Aromatizing Steroids For Breast Cancer
Quick Details:
Product Name:Formestane
Other name:Lentaron; 4-hydroxy-androst-4-ene-17-dione; 4-hydroxy-delta(sub4)-androstenedione
CAS register number:566-48-3
Molecular formula: C19H26O3
Molecular weight: 302.41
Molecular structure:
Melting point: 199-202°C
Assay: 99%
Description:
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.
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