local anesthetic Tetracaine

• Product Namelocal anesthetic Tetracaine
  CAS No.94-24-6
  Purity99%
  Min Quantity1000Kilograms
  Price1~1000
• View Contact Detail

• 
  Molecular Structure

Detailed Description

Tetracaine
CAS:94-24-6
Synonyms:2-(Dimethylamino)ethyl 4-(butylamino)benzoate;2-(Dimethylamino)ethyl p-(butylamino)benzoate;2-Dimethylaminoethylester kyseliny p-butylaminobenzoove;2-dimethylaminoethylesterkyselinyp-butylaminobenzoove;2-dimethylaminoethylp-butylaminobenzoate;4-(butylamino)-benzoicaci2-(dimethylamino)ethylester;amethocaine;Anetain
Molecular formula:C15H24N2O2
Molecular weight:264.36
Purity:99%
State:solid
Certification:USP/ISO9001
Apperance:White crystalline powder
Usage:Tetracaine is a topical local anesthetic for the eyes. Tetracaine works by interfering with entry of sodium ions into nerve cells. This reduces the ability of nerves to generate an impulse and send pain sensations.
Description:
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Application:
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5? (per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. A systematic review and meta-analysis of randomised controlled trials investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties - however it did not find a statistically significant improvement in first attempt cannulations.
Packing:
Discreet packing ways as your requirement, 100% go through.
Storage:
Store in cool and dry area and keep away from direct sunlight.
Advantage:
1. Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.
2. Payment method: T/T, Western union, Moneygram.
3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.
4. We have stock, so we can delivery quickly at the very day when receive the payment.
5. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
6. A discount would be given when you make a large order.
• 
• local anesthetic Tetracaine