Ethisterone
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Molecular Structure
Detailed Description
Ethisterone
Synonym: Ethinyltestosterone,Progestoral
CAS NO: 434-03-7
M.F.: C21H28O2
M.W: 312.45
Purity:min98%
Packaging: 1kg/tin
Appearance: White or kind of white crystalline powder
Usage: Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone
Description:
Ethisterone is a metabolite . Ethisterone is a progestogen hormone. The first orally active progestin.This compound belongs to the class of organic compounds known as androgens and derivatives. These are
3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
Potent progestin. Progesterone and androgen receptor antagonist.
Ethisterone is a progestogen that counteracts estrogenic proliferative effects on the endometrium.
Ethisterone is a progestogen hormone being considered to treat prostate cancer
Application:
Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. CMA acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase. It suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production. CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness and increases the viscosity of cervical mucus.
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yc2016
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