Felodipine
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Molecular Structure
Detailed Description
Packaging & Delivery
Packaging Detail: 25kg/Drum
Delivery Detail: 7 days after prepayment
Specifications
Felodipine is a 1,4-dihydropyridine small molecule antagonist and calcium channel protein inhibitor. Antagonism of the vascular L- type (long-lasting) calcium channel decreases intracellular calcium concentration, softening the tone of vascular tissue anddecreasing the peripheral resistance upon the blood stream, effectively decreasing systemic arterial blood pressure withoutaffecting myocardial contractility. Felodipine is described to inhibit cytokine-induced NO and superoxide production as well as
cytokine-induced NO synthase (NOS) mRNA induction, and is suggested to act as a scavenge superoxide and not an inhibitor of inducible NOS induction. This indicates that Felodipine further protects the vasculature againstendogenous free radical generation during inflammatory responses.
Name: Felodipine
Cas No:72509-76-3
MF:C18H19Cl2NO4
Use: calcium antagonist
Appearance: white crystals
Specification
Product Felodipine
CAS NO 72509-76-3
Standard EP5.0 USP28 CP2005
Appearance: light yellow to white crystalline powder Melting point:141~145°C Assay≥99.0%, Total impurity<1.0%, Individual impurity<0.5%
Molecular Formula C18H19Cl2NO4
Molecular Weight 255.08
Description off-White or white crystal or crystalline powder
Package 25KG/drums
Application For the treatment of hypertension, ischemic heart disease, heart failure and other diseases
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- Felodipine