procaine hydrochloride
Product Name:procaine hydrochloride;procaine HCL;procaine;naucaine
CAS:51-05-8
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
Appearance:white crystalline powder
Usage:local anesthetic used as a pharmaceutical intermediate for infiltration anesthesia, nerve block
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
The routes of administration and concentrations are: for local infiltration use 0.25% to 0.5% (via dilution) and for peripheral nerve blocks use 0.5% (via dilution), 1%, and 2%. (See DOSAGE AND ADMINISTRATION for additional information.)
Application:
Tetracaine is a topical opththalmic anesthetic used to relieve the pain the skin and as an eye drops for minor eye operations. It prevents voltage-sensitive release of Ca2+ from sarcoplasmic reticulum and can be used as a spinal anesthetic.
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