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(E)-3-(4-methylphenyl)prop-2-enoic acid

  • CAS No:1866-39-3 (E)-3-(4-methylphenyl)prop-2-enoic acid
    Molecular Structure

    Detailed Description

    4-Methylcinnamic Acid
    CAS No. : 1866-39-3
    Properties : White Crystalline Powder
    Purity : 99%
    Packaging : 25kg
    Storage method : Store below 30°C
    Usage :
    It is used to synthesize methyl p-methyl cinnamate. Methyl p-methyl cinnamate is mainly used to synthesize p-bromomethyl cinnamate as the upstream raw material of the antithrombotic drug Ozagrel sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After condensing with imidazole at room temperature in the acid salt, alkaline hydrolysis was performed to obtain the antithrombotic drug ozagrel sodium, with a total yield of 67%.