Suzhou MyLand Pharm&Nutrition Inc.

Suzhou MyLand Pharm&Nutrition Inc.

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  • Company Name: Suzhou MyLand Pharm&Nutrition Inc.
  • Street: No.100,Jinmen Rd. Suzhou
  • City: Suzhou
  • Province/state: Jiangsu
  • Country/region: China
  • Contact Person: Ms.Brenda Zhou
  • Department: Sales
  • Tel: 86-512-66702819
  • Fax: --
  • Email:
  • Chat with supplier using
    frankfan169@hotmail.com

Coluracetam

  • CAS No:135463-81-9 N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,<br />3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide
    Molecular Structure

    Detailed Description

    Product name:Coluracetam
    Chemical name: N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide.
    CAS:135463-81-9
    Purity: 99%
    Appearance: white crystalline powder
    Package: 1kg/bag.

    Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
    Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
  • Coluracetam
  • Coluracetam