Phenacetin
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Molecular Structure
Detailed Description
CAS 62-44-2 Phenacetin
Alias:Phenacetinum,Acetophenetidin,4'-Ethoxyacetanilide;,4-Acetophenetidine,Para-Acetophenetidide
Assay:99%
CAS:62-44-2
Molecular Formula:C10H13NO2
Molecular Weight:179.2158
Appearance:white flash scaly crystalline powder
Standard:BP68
Melting Point:134~137℃
Solubility:Dissolved in ethanol or chloroform, slightly soluble in boiling water , slightly dissolve in the water.
Usage:Antipyretic analgesic active pharmaceutical ingredients
Possible side effects:
1)Long-term use of phenacetin can damage the kidneys, and even induce cancer.
2)Other possible side effects include cyanosis reaction and hemolytic anemia.
Known mechanism of action:Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.
It is metabolised in the body to paracetamol (acetaminophen).
- Phenacetin