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Cytarabine

  • CAS No:147-94-4 4-amino-1-[(2R,3S,4S,5R)-3,<br />4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
    Molecular Structure

    Detailed Description

    Cytarabine
    Synonyms Cytosine arabinoside; 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone; Arabinocytidine;
    Molecular Formula C9H13N3O5
    Molecular Weight 243.22
    CAS Registry Number 147-94-4
    EINECS 205-705-9
    Melting Point:212 - 213 C
    Flash Point:283.8 °C
    Solubility:Soluble
    Appearance: white tiny aciform crystalline powder
    Uses: Cytarabine is used to treat acute leukaemias, some head and neck cancers and non-Hodgkin's lymphoma (NHL). This drug is one of a group of chemotherapy drugs called anti-metabolites. Anti-
    metabolites are similar to normal body molecules but they are slightly different in structure. These differences mean that anti-metabolites stop cells working properly instead of helping them. Anti-
    metabolites often stop cells making and repairing DNA. Cancer cells need to make and repair DNA in order to grow and multiply.