Levamisole hydrochloride
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Molecular Structure
Detailed Description
CAS 16595-80-5 Levamisole hydrochloride
Levamisole;Levamisole hydrochloride;L-Tetramisole
levamisole hydrochloride
Appearance:White or almost white crystalline powder crystalline granular powder
Molecular Formula:C11H12N2S.HCl
Molecular Weight:240.75
CAS No. 16595-80-5
Specification:EP/USP/CP
Storage:Keep container tightly closed in a cool, well-ventilated area.
Pharmacodynamic
Properties Levamisole refers to Levo tetramisole, it is the Levo Isomer of tetramisole. It can selectively inhibit succinate dehydrogenase in parasite’s muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite’s muscle metabolism lacks of oxygen and leads to decreasing of energy.
L-isomer is active against helminthes with 1-2 times higher active efficiency and lower toxic and side effects than tetramisole. It is a broad spectrum anthelmintic with a very good activity against roundworms, hookworms, whipworms, and strongyloises stercoralis. It is an immunomodulator and has effect on rheumatic disorders.
Levamisole is also a good alternative in cases of benzimidazole resistance.
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4,use:
It can selectively inhibit succinate dehydrogenase in parasite’s muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite’s muscle metabolism lacks of oxygen and leads to decreasing of energy. Levamisole is also a good alternative in cases of benzimidazole resistance.
5,Specification:
Assay 98.5~101.0%
Acidit 3.0 4.5
Specific Optical Rotation -121° -128°
Related Substances Meets the requirements
Heavy Metals 0.002%MAX
Loss on Drying 0.5%MAX
Sulphated Ash 0.1%MAX
- Levamisole hydrochloride
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