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Dextromethorphan Hydrobromide

  • CAS No:6700-34-1 Dextromethorphan hydrobromide monohydrate
    Molecular Structure

    Detailed Description


    Product Name:Dextromethorphan Hydrobromide
    Alias: Romilar,dextromethorphan,Demorphine,Dormetan
    CAS No.: 125-69-9
    EINECS No.: 204-750-1
    MF: C18H26BrNO
    MW: 352.31
    Purity: 98.0%
    Appearance: White or kind of white crystalline powder
    Grade:Pharmaceutical Grade

    Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

    DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.

    DXM Effect

    DXM has dissociative effects, somewhat similar to ketamine and PCP. The main effects are those of dissociation (separation of mind and body), which include:

    Double vision and no perception of depth (eyes are not able to focus)
    Altered kinesthetic sense (distorted perception of gravity and movements)
    Overall reduction of external stimuli (loosens the connection between mind and body, can lead to out-of-body experiences)
    Total loss of reality awareness (dissociative anaesthesia - at high doses)
    Euphoria
    Emotion amplification
    Hallucinations (closed-eye visuals, vision trails and increased awareness of color, flanging of sound)
    Music appreciation