ChemScene, LLC

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  • Company Name: ChemScene, LLC
  • Street: 11 Deer Park Drive, Suite 102D Monmouth Junction, NJ 08852
  • City: Monmouth Junction
  • Province/state: New Jersey
  • Country/region: United States
  • Contact Person: Ms.James Gao
  • Tel: 732-484-9848
  • Fax: --
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GDC-0973;XL-518; GDC 0973; XL 518

    Detailed Description

    GDC-0973(XL-518; GDC 0973) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Inappropriate activation of the MEK/ERK pathway promotes cell growth in the absence of exogenous growth factors.