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Irinotecan

  • CAS No:97682-44-5 Irinotecan
    Molecular Structure

    Detailed Description

    Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death.https://www.bocsci.com/irinotecan-cas-97682-44-5-item-84-101283.html
  • Irinotecan
  • Irinotecan