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Darunavir

  • CAS No:206361-99-1 [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl]<br />N-[(2S,<br />3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-<br />phenylbutan-2-yl]carbamate
    Molecular Structure

    Detailed Description

    Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. https://www.bocsci.com/darunavir-cas-206361-99-1-item-62615.html


  • Darunavir
  • Darunavir