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Cyclosporin D

  • CAS No:63775-96-2 (3S,6S,9S,12R,15S,18S,21S,24S,30S)-33-[(E,1R,<br />2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,<br />9,18,24-tetrakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13,<br />16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,<br />29,32-undecone
    Molecular Structure

    Detailed Description

    A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A-cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxid